While all proposals related to the overarching focus on the impact of COVID-19 on children and adolescents in California will be considered, CPR³ will prioritize applications that:

1. Focus on children and adolescents who have been disproportionately impacted by the pandemic, including but not limited to individuals who have pre-existing conditions and disabilities, rely on social services, live in rural or underserved settings, or have ongoing unmet social needs such as unstable income, housing, food insecurity, etc.
2. Have direct applicability to inform COVID-19 and future infectious disease pandemic interventions, programs, and policies, with an emphasis on strengths, resilience and best practices
3. Have the potential to inform or align with efforts of other state initiatives (e.g., CalAIM, ACEs Aware, Children and Youth Behavioral Health Initiative), as well as school health initiatives
4. Develop methods that advance and harmonize the monitoring and evaluation of health, educational, or social outcomes related to child/youth recovery and readiness

Applications that incorporate a life-course approach that acknowledges the complex roles of social determinants of health, including systemic and structural racism are encouraged. Applications may include research among key individuals who directly influence child well-being, such as caregivers, family members, educators, and providers – as well as the systems in which they are interconnected.

CPR³ will not consider applications related to the following:

• Basic science related to SARS-CoV-2
• Clinical research solely related to COVID-19 symptoms
• Vaccine or diagnostic development
• New randomized controlled trials or longitudinal cohorts*
• Studies that exclude Californian geographies

​*Nested studies that leverage existing or ongoing randomized controlled trials or longitudinal cohort studies will be considered if they are responsive to the RFP topic area and are feasible to execute within the award period.